Think you know every sandwich worth knowing? From the famous Philly cheesesteak to the New Orleans po’ boy, many regional specialties have gained national recognition. However, hidden across America’s diverse landscape lie lesser-known culinary gems that never quite made it beyond their home borders. Practically every region has its own beloved sandwiches, and sometimes you can’t even find them beyond a particular city or neighborhood.
These regional treasures tell fascinating stories of immigrant communities, local ingredients, and cultural adaptation. They represent authentic American food culture at its most genuine level. Let’s dive into seven remarkable sandwiches that deserve your attention, each carrying the unique flavors and history of their birthplaces.
The Runza – Nebraska’s Beloved Bread Pocket
A runza (also called a krautburger, or kraut pirok) is a yeast dough bread pocket with a filling consisting of ground beef, cabbage or sauerkraut, onions, and seasonings. This Nebraska staple has deep roots in Eastern European immigration history. The runza sandwich originated from the pirog, an Eastern European baked good or more specifically from its small version, known as pirozhok (literally “little pirog”).
In 1949, Volga German descendant Sally Everett (née Brening) from Sutton, Nebraska, reportedly converted the meat and cabbage-filled sandwich into a fast food and a Nebraska staple. Krautrunsa, an archaic name for the bierok, became runsa, which became Runza. The runza is a regional cuisine of Nebraska, with some commentators calling it “as Nebraskan as Cornhusker football.”
Runzas are as much a part of Nebraska culture as Cornhusker football. At a single home game in Lincoln, more than 10,000 sandwiches are sold – about one for every nine fans in the stadium! Today, the Runza restaurant chain continues to serve these rectangular bread pockets throughout the Midwest. The combination of seasoned ground beef, cabbage, and onions wrapped in fresh-baked bread creates a hearty, satisfying meal that remains virtually unknown outside the region.
The St. Paul Sandwich – Missouri’s Chinese-American Creation
St Louis is home to several regional American sandwiches – it’s one of the last bastions of the once popular fried-brain sandwich, and it’s home to the St Paul: an unusual Chinese-American sandwich composed of an egg foo young patty (egg, onion and bean sprouts) with lettuce, tomato, onion, pickles and mayonnaise between two slices of white sandwich bread. Reportedly invented by a chef hailing from Minnesota – hence the other saint in the name – the St Paul was an attempt by Chinese restaurants in the 1940s to attract local customers unaccustomed to Chinese cuisine.
Unlike what its name may suggest, the St. Paul sandwich’s only connection to Minnesota’s Twin Cities is believed to be an homage by the man often credited with its creation. According to one account, St. Paul native Steven Yuen may have crafted this egg-foo-young-starring handheld in St. Louis, Missouri, as a menu item in the 1940s at his restaurant, Park Chop Suey, though the sandwich’s exact origins remain disputed. This fascinating fusion represents early Chinese-American adaptation to local tastes.
The sandwich consists of a crispy egg foo young patty topped with fresh vegetables and mayonnaise on white bread. Region: St. Louis · Funny enough, the St. Paul sandwich can only be found in St. Louis, not Minnesota. It was created by the city’s Chinese-American immigrants at their restaurants in the area. An egg foo yung patty made with eggs, sprouts, and often meat, is sandwiched between white bread slices with mayonnaise, lettuce, tomato, and pickle. Despite its unique appeal, this sandwich remains firmly rooted in St. Louis Chinese-American restaurants.
The Horseshoe Sandwich – Illinois’ Open-Faced Giant
Range: Restricted to Springfield, Illinois and the surrounding area · An open-faced sandwich composed of two slices of toasted bread topped with two hamburger patties and a whopping pile of french fries all smothered in a cheese sauce, obviously, the horseshoe isn’t the prettiest or the healthiest sandwich in America. For the health conscious sandwich lover, there’s the ‘pony shoe’ with just one slice of bread and one hamburger patty.
In 1920s Springfield, Illinois, a sandwich was born that defies traditional norms in an open-face style, piling ingredients high with some farrier-inspired nomenclature. Its name is drawn from the shape of the piece of ham that was originally placed on the sandwich. Chef Joe Schweska is credited with crafting the first horseshoe sandwich at the Leland Hotel. However, the inspiration is said to have come from his wife, Elizabeth, who’d suggested utilizing Welsh rarebit sauce for an open-face design.
From there, Schweska assembled his sandwich, topping slices of toasted bread with ham cut from the bone before adding a heaping helping of french fries – considered the nails to the horseshoe. After that, the cheese sauce is poured on the entire dish, and it’s served on a sizzling platter dubbed the anvil. This massive creation challenges any notion of what constitutes a proper sandwich, yet remains a beloved Springfield tradition nearly a century after its invention.
The Beef on Weck – Buffalo’s German-Inspired Classic
Primarily found in western New York, the “weck” in this sandwich comes from the bread it’s served on: a kümmelweck roll. The German-style roll topped with salt and caraway seeds is loaded up with thinly-sliced beef, topped with horseradish, with half of the bun taking a dip in some salty, delicious au jus. This Buffalo specialty represents the city’s substantial German immigrant heritage.
The beef is straightforward, but what the heck is weck? It’s the shortened local name for a kummelweck roll: a German-style a soft roll topped with salt and caraway seeds. To make the sandwich, dip half of the split roll in beef jus, and pile on thinly sliced rare beef and horseradish. Salty, spicy, messy and designed to be eaten with beer, the Beef on Weck proves that Buffalo is about more than chicken wings.
The combination of tender rare roast beef, spicy horseradish, and the distinctive caraway-seed roll creates a unique flavor profile. A favorite of German immigrants to upstate New York, the Weck is a roast beef sandwich on a salt and caraway seed-encrusted kümmelweck roll. The beef is often served rare and sometimes with mustard, but pickles and horseradish should always be available. Despite Buffalo’s growing food reputation, this Germanic sandwich remains largely unknown outside western New York.
The Chow Mein Sandwich – New England’s Fusion Marvel
Most of the country is content to chow down on chow mein all by its lonesome, but at some point, Bay Staters realized that you can make a great thing even better by turning it into a sandwich. Voila! The chow mein sandwich was born. It’s served in Chinese-American restaurants in Massachusetts and Rhode Island, and consists of fried noodles in a brown gravy sauce with pork, chicken, or vegetables on a hamburger bun.
This unusual creation represents another example of Chinese-American culinary adaptation to local preferences. The sandwich features crispy fried chow mein noodles smothered in brown gravy and protein, all served on a standard hamburger bun. The textural contrast between the crispy noodles and soft bun creates an unexpected but satisfying combination.
Found primarily in Fall River, Massachusetts, and surrounding areas, this sandwich reflects the practical ingenuity of immigrant communities adapting their traditional dishes to American dining habits. The chow mein sandwich proves that fusion cuisine existed long before it became trendy, representing authentic working-class innovation in the kitchen.
The Gerber Sandwich – Springfield’s Processed Cheese Delight
The Gerber was invented at Ruma’s Deli in the early 1970s. Legend has it a customer named Dick Gerber had it made to order, and some say this sandwich isn’t truly a Gerber unless you’re at the source. It’s a toasted, open-faced ham and cheese sandwich on crispy Italian bread with garlic butter. The special ingredient is the cheese – a processed Provel cheese that’s a hybrid of provolone, cheddar, and Swiss, and specific to the area.
The sandwich cousin of St Louis pizza, the Gerber sandwich is an open-faced toasted sandwich made with crispy Italian bread, garlic butter, ham and processed Provel cheese – a cheese only a local could love. A grilled ham and cheese meets garlic bread: what could be wrong with that? Nothing, unless you actually call it a ‘Gerber’ and you aren’t Ruma’s Deli, where it was invented in the early 1970s. The Gerber has spread around the area and become a local standby, but don’t call it a Gerber unless you’re at Ruma’s.
This Springfield, Illinois creation showcases the power of local food identity. The use of Provel cheese, found almost exclusively in the St. Louis area, makes this sandwich virtually impossible to replicate authentically elsewhere. While the concept might seem simple, the specific combination of ingredients and preparation creates something uniquely regional that locals defend passionately.
The Fry Bread Sandwich – Southwest’s Indigenous Heritage
While the rest of the sandwiches on this list were largely inspired and created by immigrant communities, sandwiches made with fry bread are the opposite. When the Diné Indigenous peoples were displaced and forced to walk approximately 300-450 miles to internment camps by the US government, they were given army rations of flour, sugar, lard, and salt. With it they made crispy and fluffy fry bread out of necessity. Today, you’ll find it topped with sweet ingredients like pumpkin or sugar, but the slightly sweet dough also lends itself extraordinarily well to ground beef, lettuce, tomato, and onion.
This sandwich carries profound cultural significance, representing resilience and adaptation in the face of historical trauma. When the Diné Indigenous peoples were displaced and forced to walk 300-miles to internment camps by the US government, they were given army rations of flour, sugar, lard, and salt. With it they made crispy and fluffy fry bread out of necessity. The transformation of survival food into beloved cuisine demonstrates the strength of Indigenous communities.
Today, you’ll find it topped with sweet ingredients like pumpkin or sugar, but the slightly sweet dough also lends itself extraordinarily well to ground beef, lettuce, tomato, and onion. Where to try it: You’ll find high-quality fry bread all across the Southwest, particularly on or near Native American reservations in Arizona and New Mexico. It’s most often sold at roadside stands rather than sit-down restaurants. The fry bread sandwich serves as both nourishment and cultural preservation, making it far more than just another regional specialty.
These seven sandwiches represent the incredible diversity of American regional cuisine, each telling a unique story of cultural adaptation, local ingredients, and community identity. From Nebraska’s German-influenced runza to the Southwest’s Indigenous fry bread sandwich, these hidden gems prove that America’s best food often remains deliciously local.
What do you think about these regional treasures? Have you tried any of these unique sandwiches, or do you know of other hidden regional specialties that deserve recognition?
