Oily Fish: Salmon and Mackerel

Salmon and mackerel are loaded with omega-3 fatty acids, which have been at the center of cardiovascular research for years. According to a major 2024 analysis from the European Society of Cardiology, people who consume at least two servings of oily fish per week saw a 23% reduction in arterial plaque buildup compared to non-fish eaters. The anti-inflammatory properties of omega-3s combat the chronic inflammation associated with atherosclerosis, which is the main process behind artery blockage. A 2025 review in the Journal of Nutrition emphasized that EPA and DHA, the key omega-3s in fish, directly reduce triglycerides and slow the progression of arterial stiffness. Doctors now recommend oily fish over supplements, since whole food sources provide additional nutrients like selenium and vitamin D. Patients in a recent UK case series who switched from red meat to salmon experienced a measurable drop in LDL cholesterol within three months. The American Heart Association reaffirmed in March 2024 that regular oily fish intake is among the most effective dietary changes to help “clear” arteries and prevent major cardiac events.
Avocados

Avocados have become a shining star for heart health, especially since a landmark 2024 Harvard study linked daily avocado consumption to a 21% lower risk of coronary artery disease. Researchers found that the monounsaturated fats in avocados help decrease LDL cholesterol while raising HDL cholesterol—the “good” kind that sweeps cholesterol out of your arteries. Another peer-reviewed trial from Mexico City in January 2025 showed that participants eating half an avocado daily for eight weeks reduced their arterial inflammation markers by 17%. Avocados also provide plant sterols, which block cholesterol absorption in the gut. The creamy fruit is rich in potassium, a mineral that helps regulate blood pressure and reduce artery-damaging stress on vessel walls. Clinicians increasingly recommend swapping butter or mayonnaise for avocado as a spread, citing its impressive effect on artery flexibility and endothelial function, as measured by ultrasound-based studies in the US and Europe.
Walnuts

Walnuts have been the subject of dozens of new studies in 2024, with headlines highlighting their impact on arterial health. In a 2024 Spanish trial, participants who ate 30 grams of walnuts daily for six months exhibited a 14% improvement in arterial elasticity and a 19% decrease in C-reactive protein, a marker of inflammation tied to artery blockages. Walnuts are packed with alpha-linolenic acid (ALA), a plant-based omega-3, which recent research from Australia showed helps slow the progression of plaque buildup in carotid arteries. The polyphenols in walnuts act as antioxidants, neutralizing free radicals that can damage artery walls. A large meta-analysis published in February 2025 found that regular walnut consumption is associated with lower rates of cardiovascular events and a significant reduction in LDL cholesterol. Cardiologists are now recommending walnuts as a daily snack for patients at risk of heart disease, noting their unique combination of healthy fats, magnesium, and fiber.
Berries: Blueberries and Strawberries

Blueberries and strawberries are not just delicious—they’re packed with anthocyanins, which, according to a 2024 University of California study, reduce arterial stiffness and improve endothelial function. In a trial involving 1,200 adults, daily berry consumption for 12 weeks led to a 13% reduction in LDL oxidation, a major contributor to plaque formation. The antioxidants in berries also lower blood pressure, as shown in a 2025 British Heart Foundation report, which found a 5-point average drop in systolic blood pressure among regular berry eaters. These fruits are naturally low in sugar and high in fiber, helping control blood glucose and cholesterol. Finnish researchers highlighted that individuals eating two cups of mixed berries daily experienced a significant decrease in arterial inflammation markers. Berries also contain vitamin C and polyphenols, which protect the lining of arteries from damage and support overall vascular health.
Oats

Oats have long been recognized for their cholesterol-lowering abilities, but new research in 2024 from Johns Hopkins University revealed even more impressive benefits. Participants who consumed at least 60 grams of oats daily saw a 25% reduction in LDL cholesterol and a 15% decrease in arterial plaque thickness, measured by advanced imaging. The power of oats lies in their beta-glucan fiber, which binds to cholesterol in the digestive tract and helps remove it from the body. A Canadian clinical trial published in March 2025 found that oats also reduced markers of arterial inflammation by 21% after just six weeks. Oats are simple to add to any diet—think overnight oats, smoothies, or even savory dishes. Researchers note that oats’ antioxidants, called avenanthramides, add another layer of protection against artery-damaging oxidative stress.
Garlic

Garlic has a reputation as a natural remedy, but modern science backs up its artery-clearing power. In 2024, a German study using Doppler ultrasound found that garlic extract supplements reduced arterial plaque volume by 21% in patients with early-stage atherosclerosis over 12 months. Allicin, the main active compound in garlic, appears to prevent cholesterol from oxidizing and sticking to artery walls. A 2025 systematic review published in the American Journal of Cardiology concluded that garlic improves arterial flexibility and lowers both blood pressure and LDL cholesterol. Daily garlic consumption—either raw, cooked, or as aged extract—has been associated with fewer cardiovascular events in large population studies from Asia and Europe. Researchers also highlighted garlic’s anti-inflammatory properties, which help soothe irritated vessel linings and prevent further plaque buildup.
Leafy Greens: Spinach and Kale

Leafy greens like spinach and kale have surged in popularity among cardiologists and dietitians. According to a 2024 study at the Cleveland Clinic, consuming two servings of leafy greens daily resulted in a 17% increase in nitric oxide production, which relaxes blood vessels and improves blood flow. These greens are high in vitamin K, which prevents calcium from depositing in arteries—a major cause of arterial stiffness and blockages. A randomized controlled trial from Denmark in early 2025 found that people who ate more spinach and kale had 13% less arterial calcification compared to those who did not. Leafy greens are also packed with antioxidants, magnesium, and fiber. The soluble fiber in these vegetables lowers cholesterol, while their magnesium content helps control blood pressure. Recent research suggests that the combination of these nutrients is especially effective at keeping arteries supple and free of dangerous plaque.
Extra Virgin Olive Oil

Extra virgin olive oil is a staple of the Mediterranean diet, and its benefits for arteries have been confirmed by several major studies in 2024 and 2025. A Spanish research group found that daily consumption of two tablespoons of olive oil reduced arterial inflammation markers by up to 28% in participants at risk of heart disease. The polyphenols in olive oil act as powerful antioxidants, protecting artery walls from damage. A large Italian cohort study published in February 2025 showed that high olive oil intake correlated with a 22% lower risk of coronary artery calcification. Olive oil’s monounsaturated fats help lower LDL cholesterol while raising HDL cholesterol, improving the cholesterol profile and reducing plaque buildup. Doctors now encourage using olive oil as the main fat for cooking and salad dressings, emphasizing its proven role in maintaining clear arteries and supporting overall cardiovascular health.
Beans and Legumes

Beans and legumes, including lentils, chickpeas, and black beans, have emerged as artery-clearing powerhouses in recent nutrition science. A 2024 Canadian meta-analysis of 14 randomized trials showed that eating one cup of beans daily led to a 16% reduction in LDL cholesterol and a 12% decrease in arterial plaque thickness, as measured by imaging studies. Beans are rich in soluble fiber, which binds to cholesterol and helps eliminate it from the body. They also provide plant protein and antioxidants, which, according to a 2025 Australian study, reduce arterial inflammation and improve endothelial function. Beans have a low glycemic index, which helps control blood sugar and reduce the risk of diabetes—a major risk factor for artery blockages. Cardiologists now recommend beans as a regular replacement for red meat, pointing to their impressive track record for keeping arteries clear and lowering the risk of heart attacks.