Grapefruit Juice: A Risky Mix With Medications

Grapefruit juice may seem like a healthy choice, but doctors have raised serious concerns about its interaction with common medications. Clinical research published in the British Journal of Clinical Pharmacology highlights that grapefruit juice can dangerously increase the amount of certain drugs in your bloodstream. This occurs because compounds called furanocoumarins in grapefruit block an enzyme that helps break down medicine. Medications for blood pressure, cholesterol, and anxiety are especially affected. The FDA has issued multiple warnings since 2023 about this interaction, urging patients to check with their doctors before drinking grapefruit juice if they’re on prescription drugs. Even small amounts of grapefruit juice can cause side effects like heart rhythm changes, muscle breakdown, or kidney problems. The risk is highest for older adults who are more likely to be taking these medications. Medical experts recommend avoiding grapefruit juice entirely if you take prescription drugs.
“Detox” Juice Cleanses: More Hype Than Health

Juice cleanses are everywhere on social media, promising to “detox” your body and boost your energy. However, a review by the Mayo Clinic in 2024 revealed that these cleanses can actually be harmful. Most commercial juice cleanses strip out fiber and key nutrients, leaving only sugar and water. Doctors warn that replacing real meals with juice for several days can lead to dangerous drops in blood sugar, muscle loss, and even heart palpitations. There’s no scientific evidence that juicing removes “toxins,” since your liver and kidneys already do that. The National Institutes of Health found that many juice cleanse products contained unregulated herbal supplements or laxatives, adding further health risks. For those with diabetes or kidney problems, juice cleanses can be especially dangerous.
Fruit Punch Juice Drinks: Sugar Bombs in Disguise

Fruit punch juices may sound innocent, but they’re often loaded with added sugars and artificial flavors. According to the Centers for Disease Control and Prevention (CDC) in 2024, most fruit punch drinks sold in stores contain less than 10% actual fruit juice. The majority of their sweetness comes from high fructose corn syrup, which has been linked to increased rates of childhood obesity and type 2 diabetes. In a recent study published by JAMA Pediatrics, children who drank sugar-sweetened beverages daily were twice as likely to develop metabolic syndrome as those who didn’t. Pediatricians now recommend parents avoid giving these drinks to kids altogether. The American Heart Association also warns adults to check juice labels carefully, as many “fruit drinks” are closer to soda than real juice.
Green Juice With Added Spirulina: Not Always Safe

Green juices with trendy superfood powders like spirulina are gaining popularity, but doctors are urging caution. In 2025, Consumer Reports found contaminants such as heavy metals in several spirulina supplements sold in the U.S. The FDA has not regulated these powders for purity or safety, and toxicology tests have shown that contaminated spirulina can cause liver damage. Very high levels of vitamin K in these juices can also interfere with blood-thinning medications, according to a Harvard Medical School update. People with autoimmune diseases should be especially careful, as spirulina may trigger immune system flare-ups. Health experts recommend choosing green juices made only from fresh, washed vegetables and avoiding those with added “superfood” powders unless certified safe.
Unpasteurized “Cold-Pressed” Juices: Bacterial Dangers

Unpasteurized cold-pressed juices are marketed as fresher and healthier, but the CDC and FDA have repeatedly warned about the risks of harmful bacteria. E. coli and Salmonella outbreaks traced to raw juice have caused dozens of hospitalizations in the past two years, including a widely reported 2024 incident in California. Because these juices skip the pasteurization process that kills dangerous germs, even healthy adults can be at risk for food poisoning. The FDA specifically advises pregnant women, young children, the elderly, and those with weakened immune systems to avoid unpasteurized juices entirely. Grocery stores now label raw juices with warnings, but many people still don’t realize the risks. Doctors say that pasteurized juices are a much safer choice for everyone.
Beet Juice: Not for Everyone With Blood Pressure Trouble

Beet juice has earned a reputation for boosting energy and lowering blood pressure. But a 2023 study from the American Heart Association warns that it can be risky for people already taking blood pressure medications or those with kidney problems. Beet juice is high in nitrates, which can make blood pressure drop too low when combined with certain drugs. There have also been reports of beet juice causing kidney stones due to its high oxalate content. Doctors urge people with pre-existing kidney disease or those on blood pressure meds to consult their physician before adding beet juice to their diet. While moderate amounts may benefit some, it’s not a safe option for everyone.
Apple Juice: High Sugar, Low Fiber

Apple juice is a staple in many households, but nutritionists are increasingly warning against it for children and adults. Research published by the American Academy of Pediatrics in 2024 found that apple juice can contain as much sugar as soda, yet lacks the fiber of whole apples. This can cause rapid spikes in blood sugar, which is especially concerning for people with diabetes or those at risk for metabolic disorders. The CDC also found that regular consumption of apple juice increases the risk of dental cavities in children. Because apple juice is often marketed as a “healthy” choice, many people don’t realize how little nutrition it actually provides. Doctors recommend choosing whole apples or water instead of juice for hydration and nutrients.
Store-Bought Lemonade: Hidden Additives and Preservatives

Store-bought lemonade can seem refreshing, but many brands contain a cocktail of additives, preservatives, and artificial colors. According to a 2023 Consumer Reports investigation, more than half of popular lemonades had added sodium benzoate and artificial yellow dyes, both of which have been linked to allergic reactions in sensitive individuals. The Environmental Working Group highlighted that some brands contain as much sugar as a can of cola. Doctors caution parents to read labels closely, as these additives can trigger hyperactivity in some children and may worsen symptoms for those with asthma or allergies. Homemade lemonade with real lemons and minimal sugar is a safer, healthier option.
Cranberry Juice Cocktails: Not the Health Drink You Think

Cranberry juice is often touted for urinary tract health, but most cranberry juice cocktails found in stores are far from pure. The USDA reported in 2024 that most contain less than 30% actual cranberry juice, with the rest made up of apple or grape juice concentrate and sweeteners. A study in Nutrition Reviews showed that the high sugar content in these drinks can outweigh any potential health benefits, especially for people with diabetes or those watching their weight. Doctors say real cranberry juice can help with certain infections, but only if it’s unsweetened and 100% juice. Patients are encouraged to check the label and avoid cocktails that are mostly sugar water.
Vegetable Juice Blends: Watch the Sodium

Vegetable juice blends are promoted as a way to get your daily veggies, but many are extremely high in sodium. A 2025 analysis by the American Heart Association found that popular vegetable juices can contain up to 900 milligrams of sodium per serving—almost half the daily recommended limit. For people with high blood pressure or heart disease, this can be especially dangerous. The sodium is added to enhance flavor and preserve shelf life, but it may cancel out any benefits from the vegetables themselves. Doctors recommend looking for low-sodium options or making fresh vegetable juice at home to control salt intake. Always check the nutrition facts before buying.