
A Dozen Bars That Could Reshape Chocolate (Image Credits: Unsplash)
Mondelēz International has produced the world’s first milk chocolate bars incorporating cell-cultured cocoa butter, marking a significant step toward sustainable chocolate production.[1][2] This collaboration with Israeli startup Celleste Bio addresses mounting pressures on the global cocoa supply chain, including climate disruptions and disease outbreaks that slashed production by up to 40% last year. The breakthrough demonstrates that lab-grown ingredients can match the quality of traditional cocoa, offering food giants a viable path to resilience.
A Dozen Bars That Could Reshape Chocolate
Nearly a dozen milk chocolate bars emerged from this partnership, crafted by Mondelēz using cocoa butter supplied by Celleste Bio. These prototypes met the company’s strict standards for integrity and consumption, proving the cultured butter’s seamless integration into real-world recipes.[2] Celleste’s CEO, Michal Beressi Golomb, highlighted the milestone’s importance: “In three years we’ve made unprecedented progress… We’ve validated our ingredients as drop-in replacements.”[2]
The bars deliver the familiar richness and melt-in-the-mouth sensation, thanks to the bio-identical nature of the cocoa butter. This achievement builds on Celleste’s October 2025 debut of the first chocolate-grade cultured cocoa butter, positioning the technology for rapid commercialization.[1]
Decoding the Cell-Culture Revolution
Celleste Bio extracts cells from a single premium cocoa bean and nurtures them in bioreactors, replicating ideal growing conditions without farmland or deforestation. The process yields enough cocoa butter for chocolate bars from one bean – what traditionally demands a hectare of trees – while maintaining identical texture, melt profile, and sensory qualities.[3][2]
Founded in 2022, the company combines biotech, agtech, and AI to customize products, such as adjusting melting points for specific applications. Chief Technical Officer Hanne Volpin noted: “We are on track to produce 1 ton of cocoa butter annually in a 1000 liter bioreactor from a single bean.”[2] This efficiency targets the $16 billion annual cocoa ingredient spend, where butter accounts for nearly half.[1]
Mondelēz’s Strategic Alliance Fuels Progress
Mondelēz, maker of Toblerone and Cadbury, served as both investor and design partner, providing expertise to refine the bars. The company joined Celleste’s $5.6 million funding round alongside Supply Change Capital and others, accelerating development from lab to prototype.[2]
Golomb emphasized the partnership’s role: “The need is real, and the business opportunity here is real. I get outreach from chocolate companies.” Celleste now engages multiple manufacturers interested in its butter and upcoming powder, supplementing – not replacing – conventional supplies.[3]
Navigating Cocoa’s Turbulent Supply Chain
Cocoa prices surged amid weather extremes, diseases, and labor shortages, prompting giants like Mondelēz to innovate. The $147 billion chocolate market faces ongoing volatility, with firms raising prices or exploring alternatives.[1]
Celleste’s approach offers stability:
- Land-free production reduces deforestation risks.
- Year-round output unaffected by climate.
- Traceable, consistent quality via controlled bioreactors.
- Scalable to offset shortages without recipe changes.
By 2035, Celleste aims for 50,000 tons annually – 5% of global needs – providing an “insurance policy” against disruptions.[3]
Toward a Resilient Chocolate Future
Scaling to commercial volumes remains the next hurdle, with market entry targeted within two years. Golomb envisions multiple solutions coexisting: “Global consumption is large enough to have multiple solutions.”[3] This milestone clears regulatory and performance barriers, inviting broader adoption.
- Bio-identical cocoa butter enables drop-in replacement.
- Single bean powers production equivalent to vast farmland.
- Addresses $16B market amid supply crises.
As chocolate lovers savor tradition, innovations like this promise endurance for the industry. What do you think about lab-grown cocoa in your favorite treats? Tell us in the comments.


